Propanethioamide, 2,2-dimethyl-

Propanethioamide, 2,2-dimethyl- - Names and Identifiers

Name	2,2,2-Trimethylthioacetamide
Synonyms	NSC 381432 Thiopivalamide Neopentanethioamide 2,2-DIMETHYLTHIOPROPIOMIDE 2,2,2-Trimethylthioacetamide 2,2-Dimethylthiopropionamide 2,2-DIMETHYLTHIOPROPIONAMIDE 2,2-Dimethylpropanethioamide 2,2,2-Trimethylthioacetamide, 2,2,2-Dimethylthiopropionamide Propanethioamide, 2,2-dimethyl- propanethioamide, 2,2-dimethyl-
CAS	630-22-8
EINECS	677-829-5
InChI	InChI=1/C5H11NS/c1-5(2,3)4(6)7/h1-3H3,(H2,6,7)

Propanethioamide, 2,2-dimethyl- - Physico-chemical Properties

Molecular Formula	C5H11NS
Molar Mass	117.21
Density	0.978±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	117-119℃ (ethyl acetate hexane )
Boling Point	162.1±23.0℃ (760 Torr)
Flash Point	51.9±22.6℃
Water Solubility	Soluble in water (10 g/L) (25°C).
Solubility	Chloroform, Ethyl Acetate
Vapor Presure	2.2mmHg at 25°C
Appearance	Solid
Color	White
pKa	13.33±0.29(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.513

Propanethioamide, 2,2-dimethyl- - Introduction

Nature:
2,2,2-Trimethylthioacetamide is a colorless to light yellow liquid with a special sulfur burning taste. It has a boiling point of 150-151 degrees Celsius, a density of 0.972-0.976 g/mL, and is soluble in a variety of organic solvents such as ethanol, acetone and dichloromethane.

Use:
2,2,2-Trimethylthioacetamide is commonly used as a protecting group or starting material in organic synthesis. It can react with certain compounds to form products with specific chemical properties or activities. In addition, it can also be used as a sulfur source and a methylating agent in chemical synthesis.

Preparation Method:
In general, 2,2,2-Trimethylthioacetamide can be prepared by the following reaction: fine sol sulfur and trimethylamine react at low temperature under appropriate solvent conditions to form 2,2,2-Trimethylthioacetamide.

Safety Information:
2,2,2-Trimethylthioacetamide should be careful to avoid contact with skin and eyes when using, and ensure that the operation is carried out in a well-ventilated place. It may be irritating to the human body, so appropriate protective measures are required. When stored, it should be kept in a sealed container, away from fire and oxidizing agents. If necessary, more detailed safety information should be requested from the relevant authorities.

Last Update：2024-04-09 20:52:54